Abnormal hohe subkortikale Aktivität bei Blickkontakt und Autismus

Sehr interessante Studie.

Studie Blickkontakt und Autismus

Aus der Studie:
An abnormality of the subcortical system in autism during face processing was first hypothesized by Senju and Johnson25, and our data
not only confirm this hypothesis, but specify it to a considerable degree: our direct comparison of the same dynamic facial expression
seen freely or with a fixation cross is the most direct evidence of the mechanisms by which direct eye-contact may be experienced as
stressful in autism.

ASD participants had higher pulvinar activation than controls in both conditions, and it seems that activity in this structure is less
consistently modulated by eye contact. The pulvinar can be considered as a central forebrain hub and its input from the superior
colliculus may be critical in shaping the functional specialization of the cortex during early development (for review, see ref. 46).
One of the roles of the pulvinar is to filter distracting stimuli47, and recently morphological alterations of this structure have been
reported in ASD, with an expanded surface area48. The thalamic hyperactivation evidenced here has been hypothesized as one of
the substrates of higher-order social cognition deficits in ASD, potentially through its dysregulatory impact on the dorsolateral
prefrontal cortex49. The role of the pulvinar in both the higher-order cognitive and the basic socio-affective profile in ASD will need
to be examined in future studies.

Falls jemand darüber mehr wissen will:
https://en.wikipedia.org/wiki/Pulvinar_nuclei
https://www.sciencedirect.com/topics/med...tistry/pulvinar